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apalutamide will lessen the level or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Coadministration of apalutamide, a solid CYP3A4 inducer, with medicine which can be CYP3A4 substrates may end up in lower publicity to those medications.Been making use of it for some time, I norm